Protein name:
Suppressor of cytokine signaling 2 (SOCS-2) ;
Alternative:
Cytokine-inducible SH2 protein 2 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Associates with the Elongin BC complex.
Function:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Location:
N/A
Protein Attributes:
50:
MTLRCLEPSG | NGADRTRSQW | GTAGSPEDQS | PEAARLAKAL | RELSQTGWYW |
100:
GSMTVNEAKE | KLKEAPEGTF | LIRDSSHSDY | LLTISVKTSA | GPTNLRIEYQ |
150:
DGKFRLDSII | CVKSKLKQFD | SVVHLIDYYV | QMCKDKRTGP | EAPRNGTVHL |
198:
YLTKPLYTSA | PTLQHFCRLS | INKCTGTIRG | LPLPTRLKDY | LEEYKFQV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Pig
Polyclonal Antibody for Rat SOCS-2
Polyclonal Antibody for Rat SOCS-2
Polyclonal Antibody for Rat SOCS-2
Polyclonal Antibody for Rat SOCS-2
Polyclonal Antibody for Rat SOCS-2
Monoclonal Antibody for Rat SOCS-2
Monoclonal Antibody for Rat SOCS-2
Monoclonal Antibody for Rat SOCS-2
Monoclonal Antibody for Rat SOCS-2
Monoclonal Antibody for Rat SOCS-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Liver .